Prolotherapy Manchester, UK

Prolotherapy is a regenerative injection therapy that aims to stimulate the body's natural healing process to repair damaged ligaments, tendons, and joints, and reduce chronic pain. It involves injecting a mild irritant solution, most commonly dextrose (a sugar solution), into the affected areas. This "irritant" triggers a localized inflammatory response, which in turn encourages the growth of new, healthy tissue and strengthens weakened structures.



It's often considered a non-surgical option for individuals experiencing persistent joint or ligament pain, instability, or chronic tendon injuries that haven't responded to conventional treatments like rest, physiotherapy, or medication.

Prolotherapy Clinics in Manchester, UK


Manchester has several clinics offering prolotherapy. Here are some options to consider, based on available information:


  • MCR Pain Clinic: This private pain clinic in Manchester explicitly mentions offering prolotherapy for chronic joint and ligament pain. They highlight their expert care, natural long-term solutions, and personalized treatment plans for both privately paying and insured patients.


    • Commonly used for: Knee pain (including osteoarthritis and ligament injuries), back and neck pain, shoulder and rotator cuff injuries, tendinitis, joint instability, sports injuries, and repetitive strain conditions.

    • Contact: 0161 327 4307 (as per their website)



  • MyMSK Clinic (Manchester): This clinic offers prolotherapy injections as a non-surgical, regenerative treatment. They emphasize stimulating natural tissue repair, reducing chronic pain, and improving joint stability and function.



    • Suitable for: Chronic joint or ligament pain, joint instability or weakness, tendon or ligament injuries, conditions like tennis elbow, plantar fasciitis, or Achilles tendinitis.

    • Cost: Approximately £320 per injection (some areas may require 3 sessions).

    • Contact: 0333 772 9655 (as per their website)



  • ProHealth Clinic (Manchester Branch): This clinic has locations in London, Manchester, and Bedford, with a branch in Manchester at The Hadley Clinic, 64 Bridge Street, M3 3BN. They are an experienced clinic performing prolotherapy and prolozone therapy.

    • Benefits highlighted: Extensive experience (over 10,000 injections performed), award-winning team, use of precision biomechanical scanning technology, and personalized exercise programs.

    • Cost: Consultation and examination fee: £95. Treatment: £285 per appointment for one body area, with additional areas at £70 each.



  • Orthobiologics Clinic (Manchester / Cheshire): While they focus more broadly on "orthobiologics" which includes treatments like Platelet-Rich Plasma (PRP) and Stem Cell Therapy, they are also a clinic in the Manchester area dealing with advanced treatments for sports injuries and joint pain, which may encompass prolotherapy principles or related regenerative injections. They have locations at The Alexandra Hospital in Cheadle and Spire Regency Hospital in Macclesfield.

  • Blackberry Clinic: They have clinics across the UK, including one that lists prolotherapy for back, knee, and pubic symphysis. Their website indicates a cost of £540 per treatment for one area, with 2 areas being £810, and usually 3 treatments are required. They offer clinics in Milton Keynes, Guildford, and Oxford. While not specifically listed for Manchester, it might be worth inquiring if they have plans for a Manchester presence or if their other clinics are accessible.


What to Expect from a Prolotherapy Consultation and Treatment



  1. Comprehensive Consultation: Your treatment journey will typically begin with a detailed consultation. The specialist will assess your medical history, symptoms, previous treatments, and conduct a physical examination. They may use imaging (like X-rays or ultrasound) to help identify the precise areas of damage or instability.

  2. Treatment Plan: If prolotherapy is deemed suitable, a personalised treatment plan will be developed, outlining the number of sessions likely required (often 3-6 sessions, spaced a few weeks apart, but this varies) and the specific solution to be injected.

  3. The Injection Procedure:

    • The targeted area will be cleaned and sterilised.

    • A local anaesthetic may be applied to minimise discomfort.

    • The prolotherapy solution (commonly dextrose, saline, and sometimes a numbing agent like lidocaine) is precisely injected into the damaged ligaments, tendons, or joints. Ultrasound guidance is often used to ensure accuracy.


    • The procedure itself usually takes less than an hour.



  4. Post-Treatment Care and Recovery:

    • You might experience mild soreness, stiffness, or bruising at the injection site for a few days to a week. This is a normal part of the healing process as the controlled inflammatory response is initiated.


    • You may be advised to avoid NSAIDs (such as ibuprofen) for a period after the injection, as these can inhibit the inflammatory response that prolotherapy aims to create.

    • Gradual return to activity is usually possible.

    • A physical therapy or exercise program is often recommended alongside prolotherapy to maximise results and strengthen the treated area.

    • The full benefits typically become apparent over several weeks to months as tissue regeneration occurs.




Cost of Prolotherapy in the UK


As seen from the clinics mentioned, the cost of prolotherapy in the UK can vary:

  • Per Injection/Session: Prices can range from approximately £285 to £540 per injection per area.

  • Consultation Fees: An initial consultation fee, typically around £95 to £265, is often separate from the injection cost.

  • Courses of Treatment: Many conditions require multiple sessions (e.g., 2-6 treatments), so the overall cost will be higher than a single injection.


It's important to clarify the full cost with the clinic, including any consultation fees, follow-up appointments, and whether the quoted price is per injection or for a course of treatment. Private medical insurance may not always cover prolotherapy, so checking with your provider is recommended.

Important Considerations



  • Evidence Base: While many patients report positive outcomes, it's worth noting that the scientific evidence for prolotherapy's efficacy is still evolving, and some studies have found inconclusive results.

  • Qualified Practitioners: Always ensure you seek treatment from a qualified and experienced healthcare professional, such as a doctor specialising in pain management or sports medicine, who is skilled in performing prolotherapy injections.

  • Individual Assessment: Prolotherapy may not be suitable for everyone. A thorough assessment by a specialist is crucial to determine if it's the right treatment option for your specific condition.

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